Association between blood pressure variability and carotid artery plaque and coronary artery diseas in primary hypertension patients
TIAN Ying
LU Rui
DONG Lei
LIU Si-ren
Abstract：Objective To investigate the association between blood pressure variability and carotid/coronary artery atherosclerosis in hypertension patients.Methods All 126 primary hypertension patients admitted in our hospital from October 2010 to October 2012 were enrolled; results of 24 h ambulatory blood pressure,carotid artery ultrasound and coronary arteriography were recorded and analysed.Results ①24 h ambulatory blood pressure and carotid artery plaque:the average systolic pressure and systolic variation were significantly higher compared with carotid artery atherosclerosis negative group [(145 ± 15)mm Hg vs (116 ± 10)mm Hg (1 mm Hg =0.133 kPa),(0.09 ±0.03) vs (0.07 ±0.01),all P ＜0.05],while the average diastolic pressure and diastolic variation were not different between the two groups(P ＞ 0.05) ; ②24 h ambulatory blood pressure and coronary artery diseas:systolic variation and diastolic pressure were significantly higher compared with group without coronary artery disease [(0.09 ±0.02) vs (0.07 ±0.02),(68 ±6)mm Hg vs (71 ±6)mm Hg,all P ＜0.05],while the diastolic variation were not different between these two groups(P ＞ 0.05) ; logistic regression analysis indicated that systolic variation was associated with coronary artery disease(r =3.719,P =0.025).Conclusion Blood pressure variability especially systolic variation is associated with carotid artery atherosclerosis and coronary disease.
Keywords：HypertensionBlood pressure variabilityCoronary artery disease
Publication Date：2013-07-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 893-894 )