Efficacy of radiofrequency catheter ablation reversing frequent premature ventricular complexes
NIE Jian-ming
HAN Zhi-hong
ZHANG Ye
WANG Yun-long
WANG Ye
LI Teng-fei
REN Xue-jun
Abstract：Objective To explore whether radiofrequency catheter ablation can reverse left ventricular dysfunction.Methods Totally 35 patients for radiofrequency catheter ablation (RFCA) and 14 patients who took antiarrhythmic drugs but did not accept radiofrequency catheter ablation were enrolled.All patients were evaluated at baseline and 3-6 months followed up in terms of premature ventricular complexes (PVC),left ventricular ejection fraction (LVEF),left ventricular end-diastolic dimension (LVEDD) and left ventricular end systolic diameter (LVESD).Results The patients in both RFCA group and control group were matched in PVC,LVEF,LVEDD and LVESD at baseline [(24 ± 1 1) ％ vs (21 ± 7) ％ ; (63 ± 9) ％ vs (60 ± 6) ％ ; (50 ± 4) mm vs (49 ± 5) mm;(32 ±5)mm vs (34 ±3)mm; all P ＞0.05].Compared to baseline,the patients in the RFCA group showed significantly decreased PVC [(8 ± 11) ％ vs (24 ± 11) ％,t =6.149,P ＜ 0.01],increased LVEF [(68 ± 5) ％ vs (63 ± 9) ％,t =3.426,P ＜ 0.01] and decreased LVEDD and LVESD [(50 ± 4) mm vs (48 ± 3) mm,t =3.539,P ＜ 0.01 ; (31 ± 3) mm vs (32 ± 5) mm,t =2.665,P ＜ 0.05].However,the patients in the control group showed significantly increased PVC [(22 ± 5) ％ vs (21 ± 7) ％,t =3.180,P ＜ 0.05],decreased LVEF [(59 ± 5) ％ vs (60 ±6)％,t =2.754,P＜0.05],and increased LVEDD and LVESD[(50 ±5)mm vs (49 ±5)mm,t =5.551,P ＜ 0.05 ; (35 ± 3) mm vs (34 ± 3) mm,t =2.599,P ＜ 0.05].Conclusion Idiopathic PVGs may represent a form of cardiomyopathy that can be reversed by catheter ablation of the PVCs.
Keywords：Premature ventricular complexesCardiomyopathyRadiofrequency catheter ablationLeft ventricular dysfunction
Publication Date：2013-06-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 758-760 )