Relation between coronary plaque morphology and plaque prolapse after drug-eluting stent implantation: an intravascular ultrasound study
WU Xiao-fan
GUO Cheng-jun
YANG Ya
LIU Mei-yan
HAO Peng
FANG Dong-ping
ZHU Wei-wei
Abstract：Objective To evaluate the relationship between coronary plaque morphology and plaque prolapse(PP) after drug-eluting stent (DES) implantation assessed by intravascular ultrasound (IVUS).Methods The study group consisted of 106 patients who underwent DES implantation and pre-and post-stenting IVUS.Results Forty-four patients had 51 PP lesions and 62 patients had 89 non-PP lesions.The PP lesions had more stent number [(1.5 ±0.6) vs (1.1 ±0.3),P＜0.001],longer stentlength [(31±13)mm vs (21±8) mm,P ＜ 0.001] and higher inflation pressure [(15.3 ± 2.6) atm vs (14.1 ± 2.1) atm,P ＜ 0.001] compared with non-PP lesions.Plaque area [(13 ± 4) mm2 vs (11 ± 3) mm2,P =0.024] was larger in PP lesions than in non-PP lesions.Positive remodeling [(76.5％ (39/57) vs 56.2％ (50/89),P =0.016],plaque rupture [33.3％(17/51) vs 18.0％ (16/89),P =0.039] and attenuated plaque [84.3％ (43/51) vs 42.7％ (28/89),P ＜0.001] were significantly more often in PP lesions than in non-PP lesions.Attenuated plaque [odds ratio (OR) =2.361,95％ confidence interval (CI):1.107-4.375,P =0.003] and stent length (OR =1.722,95％ CI:1.025-2.973,P =0.015) were independent risk predictors for PP.Conclusions PP occurs in 36.4％ of coronary lesions after DES implantation.Attenuated plaque and stent length are independent risk predictors for PP.
Keywords：Coronary diseaseDrug-eluting stentUltrasonographyinterventional
Publication Date：2013-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 741-743 )