Impact of metabolic syndrome on young female patients with coronary artery disease
LIU Wei
LIU Yu-yang
LIU Yuan-yuan
YU Yi
ZHOU Yu-jie
Abstract：Objective To investigate the prevalence and clinical impact of metabolic syndrome (MS) on young female premature coronary heart disease(CHD).Methods From January 2005 to December 2011,188 CHD and 114 non-CHD young female patients (less than 45 years old) patients were included.The prevalence of MS and other coronary risk factors were compared between 2 groups.In CHD group,patients with MS and non MS were also compared for clinical features and angiographic severity.Results The percentage of MS was significant higher in young female CHD patients than that in non-CHD patients [40.4％ (76/188)vs 22.8％ (26/114),P ＜ 0.01].For patients with CHD combined with MS,more patients presented with ST elevated myocardial infarction [30.2％ (23/76) vs 17.0％ (20/112),P ＜ 0.05].Multivariant regression study showed that high densitv lipoprotein [odds ratio (OR) =0.47,95％ confidence interval(CI) =0.123-0.813),P＜0.05]and hypertension (OR=1.018,95％ CI=1.003-1.034,P ＜ 0.05) were independent predictors of CHD.Conclusions MS has a significant impact on young female CHD.HDL and hypertension are independent predictors of CHD.Young female patients with MS should be detected earlier to prevent future coronary events.
Keywords：Metabolic syndromeCoronary heart diseaseYoung femaleCoronary angiography
Publication Date：2013-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 730-732 )