Clinical efficacy of thrombus aspiration combined with tirofiban in myocardial infarction patients
WANG Shun-qiang
Abstract：Objective To investigate the clinical efficacy of thrombus aspiration combined with tirofiban in percutaneous coronary intervention(PCI) surgery.Methods All 164 patients with acute myocardial infarction were randomly divided into observation group (82 cases) and control group (82 cases).The control group received conventional PCI operation.The observation group received 10 μg/kg hydrochloric tirofiban intravenous pushed within 3 min and kept 0.10 μg/(kg · min)for 24-36 h by intravenous dripping,then received thrombus aspiration.The thrombolysis in myocardial infarction (TIMI) grade,electrocardiogram ST segment,left ventricular ejection fraction (LVEF),no-reflow and major adverse cardiovascular events (MACE) were compared between two groups.Results The observation group was significantly higher than the control group in TIMI 3,ST segment proportion and left ventricular ejection fraction [90.2％ (74/82) vs 76.8％ (63/82),85.4％ (70/82) vs 72.0％ (59/82),(64 ± 6)％ vs (52 ± 5)％,P ＜ 0.05],the observation group was significantly less than the control group in MACE and no-reflow proportion [2.4％ (2/82) vs 10.1％ (9/82),4.9％ (4/82) vs 14.6％ (12/82),P ＜ 0.05].Conclusion It might enhanced PCI efficacy with thrombus aspiration combined with tirofiban in PCI.
Keywords：Myocardial infarction,acutePercutaneous coronary interventionThrombus aspirationTirofiban
Publication Date：2013-03-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 314-315 )