Treatment of benign prostatic hyperplasia with Qianlieshutong capsule
SUN Bo
LI Hang-xu
ZHANG Xiao-yi
Abstract：Objective To observe the clinical effect of benign prostatic hyperplasia with Qianlieshutong treatment.Methods Rat model of benign prostatic hyperplasia was established by castration followed by injection of testosterone.The rats were randomly divided into 3 groups:the normal group (without building model,distilled water 5 mg/kg),the notreatment group(building model,starch capsules 0.25 g/kg),and Qianlieshutong group (building model,Qianlieshutong capsule 0.25 mg/kg).The rats were sacrificed.The prostates were sampled and weighed and the prostate index was calculated.Immunohistochemical specimens were prepared and epidermal grouth factor (EGF) were investigated.Results Bladder pressure [(6.0 ± 1.3) cm H2O (1 cm H2O =0.098 kPa],maximum bladder capacity [(2.13 ± 0.25) ml],residual urine volume [(44 ± 5) μl],and prostatic index [(2.00 ±0.30)mg/g] in Qinalieshutong group were significantly lower than those in notreatment group.From immunohistochemical specimens of EGF,EGF levels in Qinalieshutong group was (42.6 ± 7.8) ％,which significantly lower than those in notreatment group.Conclusions Qianlieshutong can decrease prostate weight of rats.Its mechanism may be related to the inhibition of prostate tissue releasing EGF.
Keywords：Benign prostatic hyperplasiaQianlieshutong capsuleRats
Publication Date：2013-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 201-203 )