Clinical observation of Kaiyu mixture treating depression
LI Ya-li
WEI Hai-feng
JIANG Feng-ying
ZHANG Lan
LI Lin
Abstract：Objective To observe the clinical efficacy of the Kaiyu mixture treating depression.Methods All 30 cases of patients with depression were treated with Kaiyu mixture.Hamilton rating scale (HAMD) and Hamilton anxiety scale (HAMA) were used to evaluate the therapeutic efficacy of Kaiyu mixture before and after drug administration.Results The scores of HAMD and HAMA in patients with depression were significantly decreased 2,4 and 6 weeks after oral administration of Kaiyu mixture compared with those before treatment [HAMD:(10.8 ±2.4),(9.0±1.9),(7.4± 1.4) scores vs (12.6 ±2.9)scores; HAMA:(9.9 ± 2.6),(8.1 ± 1.7),(6.7 ± 0.9) scores vs (11.9 ± 3.2) scores ; all P ＜ 0.05].The total effective rates after treatment for 2 weeks and 4 weeks were 23.3％ (7/30),93.3％ (28/30),and there was significant difference(P ＜0.05).No adverse reaction was found during the treatment of Kaiyu mixture.Conclusions Kaiyu mixture is safe and effective treating depression.
Keywords：DepressionKaiyu mixtureEfficacySafety
Publication Date：2013-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 43-44 )