Safety and efficacy of Danhong injection and half dose of edaravone treating acute cerebral infarction
AI Juan
WANG Lei
QIU Xiao-mei
Abstract：Objective To investigate the safety and efficacy of multiple neural protection treatment mode which consists of Danhong injection and half dose of edaravone in treating acute cerebral infarction.Methods We enrolled 138 cerebral infarction patients with onset time within 72 h and divided them into treatment group and control group.The two groups were given sodium ozagral treatment and conventional treatment; at the same time,thrombolysis,anticoagulation,reduces fiber drugs and other free radical scavenging agents were stopped.The patients of the treatment group had Danhong injection and 250 ml saline infusion,which was combined with 30 mg edaravone injection and 100 ml saline infusion everyday.One course of the treatment was 14 days.Before and after treatment,we observe the neural function defect and daily life ability to compare the efficacy and observe adverse drug reactions.Results The difference of NIHSS scores and the ADL scores between the two groups was significant (P ＜0.05).The total effective rate of the treatment group was 86.8％ (59/68) and the total effective rate of the control group was 68.6％ (48/70) ; the curative effect was significantly different (P ＜ 0.05).The adverse events rates of the treatment group and control group respectively was 5.8％ (4/68) and 4.2％ (3/70) (P ＞ 0.05).Conclusion The multiple neural protection treatment mode which consists of Danhong injection and half dose of edaravone is safe and effective in treating acute cerebral infarction.
Keywords：Acute cerebral infarctionDanhong injectionEdaravoneFree radical scavengers
Publication Date：2013-01-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 33-35 )