Analysis of the changes of fibrinogen and D-dimer in acute cerebral infarction patients
ZHANG Yong
CHEN Cai
ZHENG Qian
Abstract：Objective To observe the changes of fibrinogen and D-dimer in acute cerebral infarction (ACI) patients before and after treatment,and to investigate the clinical significance.Methods Eighty patients of ACI were chosen as the observation group; 40 patients of community healthy elderly were chosen as the control group.All patients had blood test of fibrinogen and D-dimer before treatment,3,7,14 days after treatment.The results were comparated and analyzed.Results The levels of fibrinogen and D-two dimer in normal control group were (3.5 ± 1) g/L,(0.4 ± 0.1) g/L respectively ; those in the observation group before treatment,3,7,14 days after treatment were (12.7±3.2)g/L,(1.8 ±0.3)g/L; (9.6 ±5)g/L,(1.4 ±0.7)g/L; (6.6-±3.4)g/L,(0.9 ±0.3) g/L; (3.7 ± 1) g/L,(0.6 ±0.4) g/L respectively.The index in the observation group before treatment and after treatment all increased compared with control group (P ＜ 0.05) ; compared with before treatment,fibrinogen and D-dimer in the observation group 3,7,14 days after treatment decreased (all P ＜0.05).Conclusion Fibrinogen and D-dimer have close ties with ACI.
Keywords：Acute cerebral infarctionFibrinogenD-dimer
Publication Date：2013-01-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 31-32 )