Determination of notoginsenoside R1, ginsenoside Rg1 and Rb1 in yushangling capsule by high-performance liquid chromatography medthod
AN Lin-lin
SHENG Chun-yuan
HAN Tie-yun
MA Qi-wu
YIN Cong
Abstract：Objective To establish an assay method for notoginsenside R1,ace ginsenoside Rg1 and Rb1 in yushangling capsule.Medthods C18 column was used with a mobile phase of acetonitrile-water 0-12 min( 19∶81 ),12-60 min( 19∶81→36∶64),60-71 min( 36∶64→19∶81 ) gradient elution,velocity of flow:1.0 ml · min -1 ;Column temperature:30 ℃ ; The wavelength of detecter was set at 203 nm.Results The linear range of ginsenoside R1,ginsenoside Rg1 and Rb1 was 0.0996-1.9920 μg,0.4244-8.4880 μg and 0.3923-7.8460 μg,respectively,the average recovery rate was 99.9683％ [ relative standard deviation (RSD) =1.3561％ ],99.9417％ ( RSD =0.2706％ ) and 99.3933％ ( RSD =0.7303％ ),respectively.Conclusion The method is rapid,accurate,sensitive and reliable.The results show that the method can be used to control quality of products.
Keywords：Yushangling capsuleNotoginsenoside R1Ginsenoside Rg1Ginsenoside Rb1Chromatographyhigh pressure liquid
Publication Date：2012-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)