Discussion of multiple drug resistance to pseudomonas aeruginosa
ZHAO Jian-ping
ZHOU Xiu-lan
Abstract：Objective To study the surveillance of multidrug-resistance to Pseudomonas aeruginosa (MDRPA) and to investigate drug resistance of MDR-PA.Methods A total 591 strains of Pseudomonas aeruginosa (PA) were collected from Jan.2009 to Dec.2011.11 strains resistant drugs were identified and were detected as MDR-PA.Results The highest resistance rate (34.2％) to six kinds of antibiotics is aminoglycosides and the lowest resistance rate (12.9％) was Carbapenems.Except for carbapenems-Aminoglycosides-Eneyme inhibitors compound class (18 strains),testing result of MDR-PA was in 9 teams.Other antibiotics that contained carbapenems were less than 9 strains.But the opposite MDR-PA was more than 23 strains.The resistance rate of AMP,SAM、CZO,NIT,CXA,SXT was all higher than 95.4％.LVX,CAZ,ATM,CIP,FEP and TZP was not highly sensitive to PA's antibacterial activity (resistance rate was 27.6％-35.1％).IPM had significant antibacterial activity (resistance rate is 13.7％-24.0％).Conclusions It is important to select the drug resistance isolates of cephalosporin,enzyme inhibitors compound,aminoglycosides and monocycle β-lactam antibiotic to improve the isolate rate of MDR-PA.
Keywords：Multidrug-resistantPseudomonas aeruginosaβ-lactamase
Publication Date：2012-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 1603-1605 )