Change of T2 stage rectal cancer's lymph nodes by injecting methylene blue into the inferior mesenteric artery of intraoperative
HU Feng-liang
JIN Xin
SUN Feng
CHEN Dan
ZHAO Wen-tao
Abstract：Objective To study whether injecting methylene blue into the inferior mesenteric artery(IMA)in the redical operation of T2 stage rectal cancer can harvest more lymph nodes than the conventional method.Methods From December 2004 to June 2011,43 specimens of T2 stage colorectal cancer were studied,including 23 cases of conventional method group(using the naked eye and douching specimens to get lymph nodes)in December 2004 to August 2008,and 20 cases of methylene blue injection group(injecting methylene blue into the interior mesenteric artery combined with the conventional method)in September 2008 to June 2011.Results The average lymph nodes of each patient in the methylene blue injection group were(24 ± 14)pieces,significantly more than the conventional method group(P ＜ 0.01); and the lymph nodes of ＜ 5 mm diameter was also significantly more than that in the conventional method group(P ＜ 0.01); but the average positive lymph nodes of two groups were (1.1 ± 1.0)pieces and(0.7 ± 0.6)pieces,and the difference was not statistically significant(P ＞ 0.05).Conclusion In T2 stage rectal cancer,the method of injecting methylene blue into the inferior mesenteric artery can find out many lymph nodes,and may improve the accuracy of the postoperative staging,accordingly provides the basis for the postoperative adjuvant therapy.
Keywords：Rectal neoplasmsMesenteric arteryinferiorMethylene blueLymph nodes
Publication Date：2012-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)