The effect of trimetazidine on exercise capaclty in patients with acute coronary syndrome undergoing percutaneous coronary intervention
YU Miao
ZHAO Hong-li
WANG Shuai
LI Lu
Abstract：Objective To investigate the effects of trimetazidine on exercise capacity in patients undergoing percutaneous coronary intervention(PCI).Methods A total of 88 patients treated with PCI were selected randomly:control group(41 cases) and trimetazidine group(47 cases).The exercise capacity between two groups was compared after six months with ECG exercise test.Results ECG exercise text showed that the percent of ST level of horizontal or downward sloping adding acuity over 0.1 mV after exercise,during or after exercise and duration time ＞1 min was lower than that of control group(13.0％ vs 20.0％,P =0.025);the percent of convex shape of ST elevation was lower than that of control group(4.3％ vs 10.0％,P =0.011);the percent of typical angina was lower than that of control group(8.7％ vs 17.5％,P =0.012);the percent of U wave inversion was significantly lower than thai of control group(6.5％ vs 17.5％,P =0.000);the percent of severe arrhythmia was lower than that of control group(8.7％ vs 15.0％,P =0.016);the percent of T-wave inversion or two-way was lower than that of control group(13.0％ vs 25.0％,P =0.009);the percent of systolic blood pressure before exercise or preceding exercise down more than 10 mm Hg was lower than that of control group(8.7％ vs 15.0％,P =0.016).Conclusion Trimetazidine can improve the patient`s exercise capacity after PCI.
Keywords：Acute coronary syndromeExercise capacityTrimetasidine
Publication Date：2012-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)