The relationship between the blood sugar fluctuations and adverse events during the acute coronary syndrome percutaneous coronary intervention treatment
MA Li-ping
ZHAO Lei
LI Quan-min
Abstract：Objective To analyze the correlation of blood sugar fluctuations and prognosis of post-operative percutaneous coronary intervention (PCI) patients.Methods Totally 1723 patients admitted for PCI incorporated with diabetes and treated with PCI in the Department of Cardiology of our hospital from January to December 2009 were reviewed.According to adverse cardiovascular events and death,there were 84 patients in adverse events group and 1639 patients in no adverse events group.The blood glucose was monitored at least four times every day during the hospital stay.Based on the highest daily blood glucose and the lowest blood sugar,largest amplitude of plasma glucose excursions( LAGE),the standard deviation of blood sugar and means ofLAGE were computed for three days after operation.The correlation of blood glucose fluctuations and numbers of adverse cardiovascular events and death was observed.Results Mean blood glucose(MBG) in adverse events group and no adverse events group was 10.7 ± 2.2 and 1 1.3 ± 1.5 respectively.The standard deviation(SD) for the two groups was 3.6 ± 1.4 and 1.73 ± 0.7 respectively.The LAGE for the two groups was 1 1.3 ± 3.5 and 7.6 ± 2.4 respectively.There is no statistically significant difference between the two groups (P ＞0.05) in MBG; SD of the adverse events group was higher than the no adverse events group,the difference is statistically significant( P ＜ 0.05 ).LACE of the adverse events group was significantly higher than that of the no adverse events group (P ＜ 0.01 ).Conclusion Post-operative diabetic patients receiving PCI have large fluctuations in blood sugar,which may increase adverse cardiovascular events and mortality rate.
Keywords：Acute Coronary SyndromeDiabetes MellitusAngioplastyBalloonCoronaryBlood Glucose FluctuationsCardiovascular Events
Publication Date：2012-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)