The efficacy of intensive reduction of blood pressure for the treatment of cerebral hemorrhage
CHEN Yan-lei
CHEN Zheng
Abstract：Objective To study the safety and efficacy of intensive reduction of blood pressure for the treatment of acute cerebral hemorrhage.Methods A randomized control trial enrolling 50 consecutive patients with intracerebral hemorrhage admitted from March 2010 to December 2010 were randomly assigned to intensive blood pressure reduction group ( n =28) or guidelines blood pressure reduction group (n =22) (tho guidelines set by American Association of cardiologists).In the intensive reduction group,the systolic pressure was reduced immediately to lower than 140 mm Hg,while the blood pressure was reduced to that just below 180 mm Hg in guideline reduction group.The size of the hematoma was measured 24 h after treatment by CT scans.The outcomes were statistically analyzed with SPSS version 17.0 software.Measurement data were analyzed with t -test while numeration data were analyzed with chi square test.Results The mean values of proportional enlargement of hematoma were 7.1％ in the intensive group and 36.4％ in the guidelines group 24 hours after treatment (P =0.012).Conclusion Controlling blood pressure actively can decrease ratio early enlargement of hematoma in patients with hypertensive cerebral hemorrhage.
Keywords：HypertentionCerebral hemorrhageHematoma enlargementBlood pressure reduction
Publication Date：2012-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)