High-performance liquid chromatography and diode array detector-based method to detect the compatible stability of ceftezole and lornoxicam
CHEN Fu-chao
FANG Bao-xia
SHI Xiao-ya
ZHU Jun
Abstract：Objective To investigate the compatible stability of ceftezole injection and lornoxicam injection in 0.9％ sodium chloride injection.Methods At the room temperature (25 ± 1 ) ℃,the concentrations of ceftezole sodium and lornoxicam in the mixture solution were determined for the first 6 hours by a High-performance liquid chromatography-and diode array detector-based method.The visual appearance and pH value were also monitored.Results No significant differences were found in the content,colour and pH value for the mixed solution determined at different time within 6 hours after mixing at room temperature.Conclusion At room temperature,the ceftezole injection and lomoxicam injection are stable in 0.9％ sodium chloride injection for 6 hours.
Keywords：Ceftezole sodiumLornoxicamHigh-performance liquid chromatographyCompatibilityStability
Publication Date：2012-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)