Clinical observation of various matastatic bone cancers treated with incadronate
LAN Pei-li
MENG Ling-xin
Abstract：Objective To investagete the clinical efficacy and safety of incadronate in treatment of patients with pain of various matastatic bone cancer.Methods A randomized and parallel comparative trial was performed in 66 patients with pain of various matastatic bone cancers.The patients were randomly divided into study group and control group:study group were given intravenous injection of acid disodium and acetaminophen xycodone; control group were given service acetaminophen oxycodone only.The efficacy and the allevated satus of incadronate and oxycodone and acetaminophen tablets were observed on seventh day,fifteenth day,thirtieth day and sixtieth day respectively.Results Compared with contral group (42.3％ ),the rate of pain relief was 92.5％ ( P ＜ 0.01 ).Visual analogue scales (VAS) decreased ( P ＜ 0.05 ) in two groups.Lumbar bone mineral density (BMD) improvement was observed in the test group( P ＜ 0.05 ).There were significant differences between the two groups regarding pain relief and VAS improvement after incadornate.Conclusion Incadornate is an effective drug in the treatment of patients with various matastatic bone cancers.
Keywords：Matastatic bone cancerIncadronate disodiumClinical observation
Publication Date：2012-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)