Curative effect of early enteral nutrition for severe acute pancreatitis
REN Jun
YU Kai-huan
MA Peng
CHEN Chen
Abstract：Objective To explore therapeutic efficacy of early enteral nutrition (EEN) for severe acute pancreatitis (SAP).Methods Fifty-eight patients with SAP were divided into the early group (30 cases) and stage group (28 cases).Both groups had early enteral nutrition or initial parenteral nutrition support treatment respectively.The hemoglobin level,fasting blood glucose level and other indicators,the score of APACHE-Ⅱ and the level of serum CRP in different time,the change of intestines and stomach function,the incidence of complication,the infection rate,the length of stay in hospital,inpatient expenditure and death rate were compared between the two groups.Results There were significant differences in hemoglobin level and fasting blood glucose level [ ( 110 ± 5 ) g/L vs ( 102 ± 18) g/L,( 6.0 ± 1.8 ) mmol/L vs ( 9.2 ± 3.6 ) mmol/L,P ＜ 0.05 ],but no differences of serum calcium,lymphocyte count,serum creatinine,serum cholesterol and amylase level were observed.Patients treated with EEN had an early recovery of intestines and stomach function.There were significant differences in APACHE- Ⅱ score,serum CRP,complications,infection rate and hospitalized days.Inpatient expenditure was lower than that with stage nutrition support (P ＜ 0.05).The rate of death had no differences between two groups.Conclusion Patients with SAP treated with EEN can decrease the length of stay in hospital with optimal therapy outcomes.
Keywords：Severe acute pancreatitisEarly enteral nutritionParenteral nutrition
Publication Date：2012-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)