Sreum uric acid concentration, blood pressure and lipids in people with impaired glucose regulation
RAO Xiao-pang
Abstract：Objective To investigate the relationship between serum uric acid (SUA),blood pressure and lipids in people with impaired glucose regulation.Methods The study had normal glucose tolerance (NGT) ( n =451 ) and impaired glucose regulation (IGR) ( n =279) patients.All participants had a questionnaire; levels of serum UA,totalcholesterol( TC ),Triglyceride ( TG),high density lipoprotein cholesterol ( HDL-C ) and fasting blood glucose (FBG) was measured.A standard 75g oral glucose torlerance test was performed in all the participants.Results The trend of SUA change in between-group was significant [ ( A group,C group,B group,D group) ; P ＜ 0.05 or P ＜0.01 ] ; after adjusting age,sex,body mass index( BMI),FBG,fasting blood glucose( PBG),the changing of TC,TG,SBP in between-group was significant [ A group,C group,B group,D group TG:( 1.85 ± 0.10),( 1.81 ±0.10),(1.45 ±0.10),(1.43 ±0.10)mmol/L;TC:(5.72 ±0.10),(5.60 ±0.10),(5.42 ±0.10),(5.12 ±0.10) mmol/L;SBP:( 142 ± 20),( 138 ± 21 ),( 135 ± 176),( 125 ± 19) mm Hg,1 mm Hg =0.133 kPa; P ＜ 0.05 or P ＜ 0.01 ] ; levels of SUA were independent risk factors for hypertension in people with impaired glucose regulation,but levels of SUA were unable.Conclusions Hyperuricemia people with impaired glucose regulation can suffer from hypertension and abnormal of blood lipid levels.Hyperuricemia may be an indepentdent risk factor which causes hypertension in people with impaired glucose regulation.
Keywords：Impaired glucose regulationSerum uric acidBlood pressureLipids
Publication Date：2012-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)