The use of central venous oxygen saturation in the weaning of mechanical ventilation
XU Hui-ling
Abstract：Objective To evaluate the predictive value of Central venous oxygen saturation (ScvO2 ) to detect extubation failure in patients with mechanical ventilation.Methods Totally 70 mechanical ventilated patients with central venous catheter were included.We measured the ScvO2 immediately before spontaneous breathing trial (SBT) and 30th min afterwards.55 patients had successful SBT.We devided these patients into two groups according to extubation success or not to analyze the relevance of the ScvO2 and the result of the wean.Results The ScvO2 and O2ER％ of 30 minutes after weaning had significant difference between two groups.The patients had ScvO2 decreased more than 6％,13 of them failed to extubation and only 2 of them succeeded.Conclusion ScvO2 decreases significantly in the patients who failed to wean.We can use decrease of ScvO2 ＞ 6％ as a predictor of the extubation failure.
Keywords：Central venous oxygen saturationSpontaneous breathing trialMechanical ventilationWeaningExtubationReintubation
Publication Date：2012-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)