Tuberculosis drug resistance and treatment analysis in Hubei Yichang
DU De-bing
JIANG Jun
LIU Zheng-fang
LUO Shi-zhen
YU Ping
CHEN Chang-yin
XIANG Qi-yun
ZHONG Jian
Abstract：Objective To analyze the tuberculosis (TB) drug resistance and treatment in Yichang.Methods From January 2002 to December 2009,the Mycobacterium tuberculosis culture-positive sputum specimens for drug susceptibility testing,statistics of drug resistance and treatment were analyzed.Results The total resistance rate was 33.4％ and the multidrug-resistant pulmonary tuberculosis (MDR-TB) rate was 16.0％.Tuberculosis drug resistance in newly diagnosed group was 18.8％.Multi-drug-resistant pulmonary (MDR) rate was 7.1％.Resistance rate in re-treatment group was 46.6％ ( MDR rate was 24.0％ ).Initial drug resistance rate was 20.1％( MDR rate was 7.1％ ).Acquired resistance rate was 87.9％ ( MDR rate was 52.1％ ).Cure rates were 94.2％and 90.3％ ( P ＞0.05 ) in initial treatment group and retreatment group respectively.Early re-treatment of MDR-TB cure rates were 72.5％ (148/204) and 60.8％ (84/143) ( P ＜ 0.05 ).Untreated MDR-TB cure rate of complete and incomplete management were 79.3％ (25/53),64.5％ (51/79) (P ＜ 0.05 ).MDR-TB retreatment complete and incomplete management of cure rates were 66.7％ ( 60/90 ),47.2％ ( 25/53 ) ( P ＜ 0.05 ).Conclusions Treatment failure cases should be based on susceptibility test results option.Full management of MDR-TB can significantly improve the cure rate.
Keywords：Tuberculosis/prevention and controlBears the medicine rateComplete management
Publication Date：2012-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)