Observation of Metoprolol's curative effect on chronic heart failure
MEI Li-fang
Abstract：Objective To observe the clinical effects of Metoprolol on chronic heart failure.Methods One hundred and eight chronic heart failure patients were randomly divided into treatment group and control group.There were 54 patients in each group.In control group,the conventional strong heart,diuresis and vascular enlarge drugs were adopted.In treatment group,Metoprolols were added and slowly increased,based on the conventional treatment.The clinical curative effect of two groups of patients before and after treatment,including improved cardiac function,heart rate,blood pressure,was compared.Results The heart rate,systolic,diastolic blood pressure,left ventrieular end-diastolic,left ventricular ejection fraction and diameter of the improvements were better than those in the control group [ respectively ( 84.3 ± 14.3 ) times/min contrasts (70.3 ± 12.4 ) times/min,( 134.6 ±19.7)mm Hg contrasts (123.8 ± 16.5)mm Hg; (83.4±12.4)mm Hg contrasts (74.6 ± 15.4)mm Hg; (42.1±6.2)％ contrasts (49.8 ±6.9)％ ; (60.2 ±6.3)mm contrasts (56.5 ±5.8) Mm,all P ＜0.01 ].The total effective rate of treatment group was higher than that in the control group [ 94.4％ (51/54) contrasts 66.7％ (36/54) ].Conclusions It is safe and effective to add suitabale dosage metoprolols based on conventional drugs of resist heart failure.It can improve cardiac function of the chronic heart failure (CHF) patients and increase the curative effect.
Keywords：Heart failureMetoprololClinical curative effect
Publication Date：2012-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)