The value of ischemia-modified albumin and heart-type fatty acid-binding protein in early diagnosis of acute myocardial infarction
XIAO Nuan
HAN Zhe
YUAN Bei
XU Jin-peng
Abstract：Objective To discuss the value of ischemia-modified albumin(IMA) and heart-type fatty acidbinding protein(H-FABP) in early diagnosis of acute myocardial infarction (AMI).Methods The variation laws were observed by continuously measuring of IMA,H-FABP,Cardiac troponin I (cTnl),Creatine kinase-MB (CKMB) and myohemoglobin (MB) of 47 patients with acute chest pain at 0,3,6,9,24 hours after admission respectively.Results The sensitivity value were 65.3％ and 69.2％,80.8％ and 92.3％,88.4％ and 96.2％ for IMA and H-FABP at 0,3,6 hours after admission respectively.The sensitivity value with the combination of IMA and HFABP were 84.6％,96.2％ and 100％.There was a remarkable difference compared with other markers.The specificity of IMA and H-FABP had no remarkable differences compared with other single markers.Conclusion The co-detection of IMA and H-FABP has high sensitivity and specificity in early phase of AMI and has the extremely vital clinical significance.
Keywords：Acute myocardial infarctionIschemia-modified albuminHeart-type fatty acid-binding proteinCardiac troponin ICreatine kinaseMyohemoglobin
Publication Date：2011-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)