The application of remifentanil, propofol and succinylcholine anesthesia combined with high-frequency jet ventilation on surgery of removing foreign body in trachea of infants

ZHENG Sheng-fa; LI Gang; QIAO Xiu-jun; CAO Han-hai

doi:10.3760/cma.j.issn.1673-4777.2011.08.028

Abstract：Objective To discuss the effect and safety of surgery of removing foreign body in trachea of infants by using remifentanil, propofol and succinylcholine anesthesia combined with high-frequency jet ventilation (HFJV). Methods Totally 30 infants receiving surgery of removing foreign body in trachea were divided into two groups randomly: study group (propofol, remifentanil and succinylcholine) and control group. Each group has 15 patients. Patients of study group were given intravenous injection of propofol, remifentanil and succinylcholine and eliminated spontaneous breathing. After inserting bronchoscope, HFJV through the side hole was applied. Patients of control group were given intravenous injection of Ⅳ ketamine, γ-sodium hydroxybutyrate, propofol anesthesia and spontaneous breathing was reserved. After bronchoscope insertion, patients absorbed the pure oxygen through the side hole. They were given HFJV when necessary. During the operation, electrocardiogram (ECG), heart rate (HR) , respiratory (RR) and pulse oxygen saturation(SpO2) were continuously monitored, and compared various changes of vital sign, the times of patient choking, breath holding, apnea, and bronchospasm, and operation time, recovery time and complications during the recovery period. Results The adverse reaction and complications during the recovery period of study group were significantly lower than those in control group(P ＜0.05). Moreover, surgery and recovery time were significantly shorter than those in control group(P＜0.05). Conclusion During the surgery of removing foreign body in trachea of infants, the propofol, remifentanil and succinylcholine anesthesia combined with HFJV is superior to the traditional anesthesia in terms of keeping spontaneous breathing in maintaining stable respiration and circulation and reducing operation time.