The relationship between red cell volume distribution width and intima media thickness in type 2 diabetes mellitus patients
ZHANG Ming-hua
ZHANG Hua
WANG Su-li
WANG Qi
LIU Ji-qin
GAO Hong-wei
TANG Qing-lin
LIU Yu
ZHOU Xin
PANG Bo
Abstract：Objective To evaluate the relationship between red cell volume distribution width(RDW) and intima media thickness(IMT) in type 2 diabetes mellitus(T2DM) patients. Methods Two hundred and twentyfive T2DM patients consecutively admitted into our hospital were divided into two groups according to whether IMT were increased or not. The baseline clinical data of the patients were collected and the relationship between RDW and IMT was evaluated. Results The age of the IMT increased group was higher than that of normal IMT group [(62.2 ± 9. 5) years vs (53. 9 ± 9. 6) years]. The proportion of patients with hypertension was higher[61.7% (111/180) vs 31.1%(14/45)] and serum creatinine was higher[(65.3 ±30.8) μmol/L vs (52.4 ± 15.7)μmol/L]. There were significant differences of age, plasma creatinine, RDW and hypertension history between the two groups (P=0.000, 0.001, 0.000, 0.000 respectively). There was significant correlation between RDW and IMT(r= 0.28, P = 0. 000). Logistic regression analysis indicated that RDW was one of the risk factors of IMT (OR = 2.272, 95% CI 1.241 -4.195, P=0.008). Conclusion RDW may be significantly related to IMT in T2DM patients and may be valuable to the prognosis.
Keywords：Type 2 diabetes mellitusRed cell volume distribution widthIntima media thickness
Publication Date：2011-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)