Analysis of the cause of goiter with non-deficiency iodine
WANG Qing-ping
ZHANG Xiang-dong
WANG Li-hong
YIN Li
XU Rui-xia
Abstract：Objective To study the cause of goiter with non-deficiency iodine. Methods Thyroid hormones and thyroid autoantibodys were determined and thyroid volumes were measured on 362 newly diagnosed outpatients with goiter. Results Among 362 cases of patients, 130 were diagnosed of Graves, 90 of hashimotos, 43 of thyroid nodules, 41 of primary hypothyroidism, 17 of subacute thyroiditis, 18 of postpartum thyroiditis and 23 of simple goiter. There were more females (P < 0.05). Patients with the thyroid nodules and the primary hypothyroidism were more elderly than other patients ( P < 0. 05 ). The positive rate of thyroid autoantibodys was 65. 7% , 60. 8% of TMAb and 58.6% of TGAb. The levels of TMAb and TGAb in both Graves and Hashimoto were higher than those in other groups (P <0.05). The levels of autoantibodys in the simple goiter were the lowest. The volume of thyroid in both Graves and Hashimoto were higher than that in other groups ( P < 0.05 ). The volumes of thyroid were correlated to the level of thyroid autoantibodys (P <0.05). Conclusion The thyroidism, especially the autoimmune thyroid diseases ( AFTD) is the prime reason for goiter with non-deficiency iodine.
Keywords：GoiterIodineAnalysis
Publication Date：2011-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)