Effect of intracoronary lirofiban on slow blood flow after stent implantation
WANG Chun-mei
ZHU Xiao-ling
AI Hui
ZHANG Qian
LI Xiang
LIU Zi-jun
Abstract：Objective To investigate the effect of intracoronary tlrofiban and nitroglycerol on slow blood flow after stent implantation during percutaneous coronary intervention(PCI).Methods Totally 201 patients with acute coronary syndrome(ACS)undergoing PCI were enrolled in this study from January 2008 to January 2011.The patients were divided into 2 groups according to intracoronary tirofiban and nitroglycerol(tirofiban group)or nitroglyc-erol only(control group).Results Tirofiban group had significantly increased risk of the rate of acute myocardial infarction,TIMI flow 0-1 before PCI[71 cases(76.3%)VS 66 cases(61.1%),47 cases(50.5%)VS 39 cases (36.1%),P=0.046,0.023],but lower rate of unstable angina pectofis(UA)than control group[22 cases(23.7%)VS 42 cases(78.9%),P=0.023].Tirofiban group had higher rate of TIMI flow 3 after PCI.Although the slight bleeding incidence in the control group Was less than that in the tirefiban group,no severe bleeding was observed between 2 groups.Conclusion Intracomnary timflban and nitroglycerol can safely and effectively reduce the incidence of slow flow in patients after stent implantation during PCI.
Keywords：Angioplastytmmluminalpemutaneous coronaryTirofibanNitroglyeerolSlow flow
Publication Date：2011-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)