The relation between serum uric acid and the severity of coronary artery lesions in young women
ZHOU Yun
SU Gong
MI Shu-hua
Abstract：Objective To study the relation between serum uric acid and the severity of coronary artery le-sion in young women. Methods One hundred and eighty-three young women patients underwent coronary angiogra-phy between January 2002 and January 2011 were selected. According to the results of coronary angiography, they were divided into three groups: the single, double and triple vessel lesions. The relation between body mass index (BMI) , systolic blood pressure( SBP) , diastolic blood pressure(DBP) , heart rates(HR) , serum uric acid(UA) , fasting blood glucose(FBG) , triglyceride(TG) , total cholesterol(TC), high density lipoprotein cholesterol(HDL-C) , low density lipoprotein cholesterol (LDL-C) with severity of coronary artery disease (CAD) were analyzed. Results The UA level in the triple vessel lesions group was significantly higher than that in the single and double vessel le-sions group[(312.62±75.86)μmol/L vs(263.88±66.08) ,(263.99±71.39) μmol/L, P<0.05]. In the mul-tiple vessel lesions group, lnTG, TC and LDL-C were significantly higher than those in the single vessel lesions group[(0.44±0.56) , (0.62 ±0.46)mmol/L vs(0.29±0.46)mmol/L;(4.68±1. 37) , (5. 60±1.63)mmol/L vs(4.14 ±0.93)mmol/L;(2. 87 ± 1.15) , (3. 76 ± 1.28)mmol/L vs(2. 48±0. 74)mmol/L] , but there was no significant difference of UA between the two groups. According to Logistic regression analysis, the factors related with the multiple vessel lesions CAD was TG, LDL-C(P<0.05) , meanwhile the UA was not an independent risk factor. Conclusion In young women patients, high UA level is related to severe coronary artery vessel lesions.
Keywords：Coronary artery lesionYoung womenUric acidCoronary angiography
Publication Date：2011-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)