Effects of thrombus aspiration during emergency percutaneous coronary intervention in acute ST segment elevation myocardial infarction patients
HUANG Wei-guang
LUO Jing-yun
ZHAO Qiang
XU Yuan-jie
CUI Jin
WU Tong-guo
Abstract：Objective To evaluate the effect of thrombus-aspiration during emergency percutaneous coronary intervention (PCI) in patients with acute ST segment elevation myocardial infarction (STEMI). Methods The STEMI patients underwent emergent PCI from June 2008 to June 2010. Fifty patients received aspiration thrombecto-my were enrolled in study group and 46 patients who only received routine PCI were enrolled in control group. The clinical data, information after operation and the follow-up data were compared between the two groups. Results There were no significant differences between two groups on baseline. In the study group, stents were directly implanted and TIMI flow grade 3 was obtained with a significant difference of no-reflow/slow flow ( P = 0. 029 ). There were lower peak serum CK-MB(P =0.031) , TnT(P = 0.023)and faster ST segment resolution(P = 0.005) in the study group. The heart failure(P = 0.025) , re-infarction(P = 0.041)and mortality(P =0.043)in the hospital were decreased in the study group. Conclusion Thrombus-aspiration is safe and has good immediate effects during emergency PCI with STEMI, which can improve myocardium perfusion and reduce myocardial necrosis.
Keywords：Acute myocardial infarctionPercutaneous coronary interventionThrombus aspiration
Publication Date：2011-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)