A case report of successful treatment of rituximab combined chemotherapy and hematopoietic stem cell transplantation for refractory diffuse large B cell lymphoma and literature review
GUO Zhi
HE Xue-peng
YANG Kai
LIU Xiao-dong
Wang Bing-ran
LIU Dan
CHEN Hui-ren
Abstract：Objective To report the clinical efficacy and safety of rimximab combined with autologous hematopoietic stem cell transplantation in a case of refractory diffuse large B cell lymphoma.Methods Clinical data of a case in rituximab combined chemotherapy and hematopoietic stem eell transplantation for refractory difluse large B cell lymphonm was analyzed.The efficacy and safety for the program with literature review were evaluated.Results The patient did not achieve remission with various chemotherapy regimens.After using autologous hematopoietic stem cell translplantation with rituximab,the hematopoietic was rebuilded successfuly,symptoms were complete reIieved,complications wero well controlled.Follow-up to November 1,2010,tIle patient was discasc-free survival.Conclusion Rituximab combined with autologous hematopoietie stem cell transplantation is a safe and effective treatment of refractory diffuse large B cell lymphoma.
Keywords：Lymphomalarge-celldiffuseHematopoietic stem cell transplantationRituximab
Publication Date：2011-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)