Changes of plasma D-dimer levels in hemorrhagic shock patients and the relation with disseminated intravascular coagulation
ZHENG Wei-guo
LI Xiao-yun
SUN Li-xia
PU Jian-yi
Abstract：Objective To explore the relation between traumatic disseminated intravascular coagulation (DIC) with the levels of plasma D-Dimer(D-D) in hemorrhagic shock. Methods Totally 58 hemorrhagic shock patients were divided into DIC group( 12 cases) and non-DIC group(46 cases). Twenty healthy people were enrolled as the control group. Venous blood was collected only one time in the control group. But in other groups, venous blood was collected on 1,3, 5 and 7 day after shock. The D-D concentrations were measured by automated latex enhanced immunoassay. Results D-D level in the DIC group and non-DIC group were both higher than those in the control group. Furthermore, D-D level in the DIC group was remarkably higher than that in the non-DIC group. The plasma D-D of the DIC group were remarkably higher than that of the non-DIC group. Plasma D-D levels had significantly positive correlations during all time phases. Conclusions The D-D levels are not only relevant to the severity of shock but also closely to the occurrence of DIC after shock. The detection of plasma D-D levels can predict the occurence of DIC.
Keywords：ShockcardiogenicDisseminated intravaseular coagulationD-dimer
Publication Date：2011-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)