Observation of nonfermenting gram-negative bacilli infection influencing mechanical ventilation in patients with pneumonia after esophagectomy
LIU Zhen-jun
LU Song
LI Yi
Abstract：Objective To observe the nonfermenting gram-negative bacilli (NFGNB)influencing mechanical ventilation in patients with pneumonia after esophagectomy. Methods Required endotracheal intubation or tracheostomy and mechanical ventilation were applied in 61 patients, of which 32 cases had NFGNB infection, 29 cases did not have NFGNB. The differences of mechanical ventilation time, ICU time, length of stay (LOS), ventilatorassociated pneumonia, tracheostomy in two groups were analyzed. Results Ventilator-associated pneumonia incidence[63.0% (20 cases)vs 21% (6 cases) ,P ＜0.01] and tracheotomy rate [53% (17 cases)vs 28% (8 cases) ,P ＜0. 05] increased in NFGNB group. During mechanical ventilation, ICU time and LOS in NFGNB patients were significantly longer than those without NFGNB [( 14 ± 10) d vs ( 7 ± 5 ) d, (9 ± 4 ) d vs ( 17 ± 15 ) d, ( 32 ± 15 ) vs (43 ± 22)d,P ＜0.05]. Logistic regression analysis showed that the double NFGNB infection were independent factors causing prolonged mechanical ventilation (P＜0. 05), OR was 6.353 (95% CI 1.203-33.549). Conclusions NFGNB postoperative infection leads to extension of mechanical ventilation time, ICU time and LOS, increased ventilator-associated pneumonia and tracheostomy rates. Particularly, double NFGNB infection causes significantly prolong the time of mechanical ventilation. Intensive prevention of postoperative pneumonia, especially NFGNB infection has important clinical significance.
Keywords：Esophageal neoplasmsPneumoniaMechanical ventilationNonfermenting gram-negative bacilli
Publication Date：2011-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)