Relevance between endogenous creatinine clearance rate and metabolic syndrome in elderly patients with type 2 diabetes
LI Mei
ZHANG Hong
ZHU Meng-yu
ZHAO Wei
Abstract：Objective To investigate the relevance between endogenous creatinine clearance rate(Ccr) and metabolic syndrome and its components in elderly patients with type 2 diabetes. Methods Totally 392 elderly patients with type 2 diabetes were divided into two groups based on with/without metabolic syndrome. Compared the changes of Ccr in the two groups. The relationship between Ccr and metabolic syndrome and its components was analyzed. Results The prevalence of metabolic syndrome in 329 elderly patients with type 2 diabetes was 56.23%;compared to N MS group, the levels of body mass index (BMI), triglyceride (TG), systolic blood pressure(SBP)and diastolic blood pressure(DBP) in MS group increased obviously, but high density lipoprotein-cholesterol(HDLnegative correlation with BMI, TG, SBP, DBP and the number of metabolism mustering(r=-0.190, -0.277, -0.156, - 0.128, -0.214, P ＜ 0.05 ). After adjusting the age, gender, the ascend duration of diabetes and glycosylated hemoglobin A1C, Ccr had a negative correlation with metabolic syndrome and it's components of TG, BMI,DBP( P＜0.05). Conclusion There is high prevalence of metabolic syndrome in elderly patients with type 2 diabetes. It helps to prevent and treat diabetic nephropathy by controlling the levels of the components of metabolic syndrome.
Keywords：Diabetes mellitustype 2Metabolic syndromeCreatinine clearance rate
Publication Date：2011-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)