Detection and analysis of adiponectin in serum of patients with lung cancer and pneumonia
ZHANG Hai-yan
HUANG Xiu-xia
PANG Bao-sen
GUO Su-liang
Abstract：Objective To study serum levels of adiponectin in patients with lung cancer and pneumonia and to explore its relationship with clinical disease and significance. Methods Enzyme-linked immunosorbent assay (ELISA) was used to detect 70 cases of lung cancer, 65 patients with benign lung diseases and 60 normal controls in the serum adiponectin levels, and the results were analyzed statistically. Results In healthy controls and benign lung disease group, serum adiponectin levels were higher than the lung cancer group. Serum adiponectin levels in healthy controls, benign lung disease group, and lung cancer group decreased in turn[(11.46 ±6.93)mg/L, (9.69 ±6.12) mg/L, (5.91±4.49) mg/L]. Between healthy control group and the lung cancer group there was significant difference (P＜0.01); between benign lung disease group and the lung cancer group there was significant difference (P＜0.01 ) too. Conclusion The low level of serum adipinectin in patients with lung cancer indicates that adiponectin is closely related with the development of lung cancer, and it might be used as an important indicator for the detection of treatment of lung cancer.
Keywords：Lung neoplasmsAdiponectinPneumoniaEnzyme-linked immunosorbent assay
Publication Date：2011-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)