The influence of subclinical hypothyroidism on C-reactive protein and microalbuminuria in patients with coronary heart disease
TU Yan-ping
LEI Meng-jue
WU Xiao-he
GONG Ai-bin
WEI Wei-rong
WANG Ling-ling
AI Wen-wei
WU Su
YAO Xiao-lu
Abstract：Objective To observe the influence of subclinical hypothyroidism on c-reactive protein (CRP) and microalbuminuria (MAU) in patients with coronary heart disease. Methods The level of serum triglyceride ( TG), total cholesterol( TC), homocysteine (Hcy), CRP and urinary MAU was measured in 80 patients with coronary heart disease (of them 40 complicated with subclinical hypothyroidism). Results The levels of TG, TC,CRP, and MAU increased significantly in the patients complicated with subclinical hypothyroidism as compared with those without subclinical hypothyroidism ([(1.7±0.8)mmol/L vs (1.5±0.5)mmol/L, ( 5.7 ± 0.8 ) mmol/L vs (4.5 ±0.7)mol/L, (4.8 ± 1.6)mg/L vs (3.1 ± 1.3)mg/L, (51.2 ±3.5)mg/L vs (42.4±4.7)mg/L]P＜0.01 or P＜0.05). Conclusions Subclinical hypothyroidism can not only affect lipid metabolism, but also increase inflammation and microalbuminuria in patients with coronary heart disease.
Keywords：Subclinical hypothyroidismCoronary diseaseC-reactive protein
Publication Date：2011-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)