Conformal radiotherapy combined with hyperthermia for advanced, unresectable pancreatic cancer
DING Zhao-jun
MENG Ling-xin
XUE Ying-jie
Abstract：Objective To evaluate the therapeutic effect of conformal radiotherapy combined with concurrent hyperthermia on advanced, unresectable pancreatic cancer. Methods Thirty-four patients with advanced pancreatic carcinoma received conformal radiotherapy with 2Gy/fraction, five fraction/week, a total dose 50-70 Gy.Meanwhile hyperthermia was performed twice a week for six fractions with 60-90 minutes/fraction. Results Totally 82.4% of the patients who suffered from pain got relief and the clinical benefit response was 82.5%. The overall response rate ( both complete and part recovery) was 77.5%, and 1-year and 2-year survival rates were 32.5% and 20.0%. Conclusion The conformal radiotherapy combined with concurrent hyperthermia is an effective approach to improve life quality and prolong survival time for unresectable pancreatic carcinoma.
Keywords：Pancreatic neoplasmsConformal radiotherapyClinical benefit reponseDiathermyPain
Publication Date：2011-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)