Treatment of secondary hyperparathyroidism with hemoperfusion and hemodialysis and nursing comprehension
LIN Li
MA Shu-fen
Abstract：Objective To observe the clearance effect of hemoperfusion associated with hemodialysis on parathyroid hormone(PTH) levels in patients of secondary hyperparathyroidism and the nursing comprehension. Methods Sixty patients on maintenance hemodialysis were randomly divided into two groups:hemoperfusion plus hemodialysis group ( HP +HD) ,hemodialysis group (HD). HD + HP group received 2 times HD + HP and 1 time HD treatment per week. HD group received 3 times HD treatment per week. Serum PTH and platelet levels were observed before and after treatment. The improvement of symptoms such as skin itching, sleeping, ache, appetite and hypertension were observed. Results Serum PTH in HP + HD group decreased significantly from (987 ± 531 ) ng/L to( 769 ± 496 ) ng/L after treatment ( P ＜ 0.05 ), but serum PTH in HD group showed no obvious change. The level of platelet showed no significant differences. The clinical symptoms improvement ratio of HD + HP group in skin itching, sleeping, ache, appetite and hypertension ( 83.3%, 26.7%, 73.3%, 80.0%, 66.7% )was higher than that in HD group(50.0%, 6.7%, 46.7%, 53.3%, 33.3% ) ,the difference is statistical significance (P ＜ 0.05). Conclusions Hemoperfusion associated with hemodialysis can safely and effectively clear PTH, improve clinic symptoms and decrease complications. At the same time sophisticated nursing very important during the treatment.
Keywords：HyperparathyroidismsecondaryDialysisPerfusionParathyroid hormone
Publication Date：2010-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)