Stability of pazufloxacin mesilate injection mixed with ornidazole and sodium chloride injection
HUANG Xiao-hua
ZHU Xue-song
ZHENG Fang
Abstract:Objective To study the stability of pazufloxacin mesilate injection and ornidazole and sodium chloride injection at ambient temperature [ ( 20 ± 1 ) ℃ ] and to supply evidence of clinical rational administration.Methods The changes of the contents of pazufloxacin and ornidazole were determined simultaneously by RP-HPLC-DAD. The changes of appearance and pH value were observed within 6 hours. Results No significant changes were found in the contents, appearance and pH value of the mixed solution within 6 hours. Conclusion Pazufloxacin mesilate injection can be mixed with ornidazole and sodium chloride injection at ambient temperature [ (20 ± 1 ) ℃ ]within 6 hours.
Keywords:Chromatographyhigh pressure liquidPazufloxacin MesilateOrnidazole
Publication Date:2010-01-01
Online Publishing Date:2026-09-14(First online date of this platform, not the publication date of the document)
CHINA MEDICINE

CHINA MEDICINE

ISTIC
ISSN:1673-4777
Year, Vol.(Issue):2010,05(12)