Effect of vinorelbine and cisplatin on non-small cell lung cancer
DAI Zhong
CAO Jun
ZHAO Hong-yan
Abstract：Objective To investigate the effect and adverse reaction of NP regimen(NVB + DDP)on nonsmall cell lung cancer(NSCLC). Methods The clinical data of 40 cases with NSCLC was collected from January 2005 to January 2010.They were treated with NP regimen(NVB 25 mg/m2,d1,d8,intravenous drip;DDP 75 mg/m2,d1～3,intravenous drip).21 days were one course and the treatment lasted for 4 courses.The short-term curative effect and adverse reaction were evaluated. Results The overall response rate was 32.5%.Grade Ⅲ and Ⅳ hematopoietic toxicity was observed in 42.5%,and peripheral nerve toxicity was 72.5%. Conclusions NP is an.effective and safe regimen on NSCLC.The toxicity and adverse reaction is relatively small,the price is relatively low,it has vast development prospects.
Keywords：Carcinomanon-small cell lungAntineoplastic combined chemotherapy portocolsAnaphylaxis
Publication Date：2010-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)