The clinical observation of L-cartnine in the off-pump coronary artery bypass graft
ZHAO Tie-fu
WANG Sheng-yu
ZHOU Qi-wen
MA Han-ying
Abstract：Objective To observe the therapeutic effect of L-carnitine in the off-pump coronary artery bypass graft. Methods Totally 160 patients recieving off-pump coronary artery bypass graft were enrolled in the casecontrol study. Results One hundred and sixty patients all survived in the perioperative period. Compared with the control group, perioperative chest tightness and palpitations were significantly less (1.25% vs 8.78% , 1.25% vs 10. 13% ) in the L-camitine group; the ST-segment changes and the incidence of new atrial fibrillation was significantly lower (3. 75% vs 10.00% , 0 vs 8.75% , 1.25% vs 11.25%) after 12, 24 h; left ventricular ejection fraction increased significantly [(57.66 ± 5.45)% vs (45.24 ± 3.43)%] after 3 months. Conclusions L-camitine is a safe and effective therapy during perioperative period of off-pump coronary artery bypass graft.
Keywords：Coronary diseaseCamitineOff-pump coronary artery bypassoff-pumpL-cartnine
Publication Date：2010-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)