The use of antiplatelet drug in the patients undergoing selected drug eluting stent implantation guided by thrombelastograph
MENG Kang
L(U) Shu-zheng
ZHU Hua-gang
CHEN Xin
GE Chang-jiang
ZHOU Yuan
SONG Xian-tao
LIU Xin
CHEN Hua
Abstract：Objective To evaluate the use of antiplatelet drugs in the eldly patients undergoing selected PCI procedure guided by thrombelastograph. Methods Two hundreds and eighty patients with the sirolmus drug eluting stent were enrolled. 136 of them were enrolled in the none-ADP guided group. The rest 144 cases were included in the ADP guided group and had modified use of antiplatelet drugs according to the ADP platelet aggregation index to obtain the eligible standard. All patients were followed up for 12 months. Results The ADP immediate platelet aggregation index reached 74% in the ADP guided group and 56% in the no-ADP guided group. The major adverse cardiac events in the ADP guided group were less than those in the no-ADP guided group. (ADP guided group vs. no-ADP guided group 4. 2% vs. 8.1% , P = 0. 05 ). All patients had no hemorrhea and severe complication of bleeding (P>0.05). Conclusions The application of antiplatelet drugs according to the ADP platelet aggregation index helps decrease the major adverse cardiac events in the patients undergoing the PCI, without increasing bleeding complications.
Keywords：Coronary vesselsPlatelet aggregationPlatelet aggregation inhibitors
Publication Date：2010-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)