Stability of potassium sodium dehydroandrographolide succinate for injection and ganciciovir for injection by HPLC-DAD
LU Lian-ying
ZHENG Fang
LI Zhi-hao
Abstract：Objective To study the stability of potassium sodium dehydroandrographolide succinate for injection and ganciclovir for injection in 5% glucose injection. Methods At ambient temperature [ (20 ± 1)℃ ], the changes of the contents of potassium sodium dehydroandrographolide succinate and ganciclovir were determined simultaneously by HPLC-DAD, and the changes of apperance, pH value were observed within 8 hours. Results Significant changes were observed in the content, apperance and pH value for the mixed solution within 8 hours.Conclusion Potassium sodium dehydroandrographolide succinate for injection cannot be mixed with ganciclovir for injection in glucose injection at ambient temperature.
Keywords：Chromatographyhigh-performance liquidPotassium sodium dehydroandrographolide succinateGanciclovirlncompatibilityStability
Publication Date：2010-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)