Clinical observation of gangliosides GM1 combined with early rehabilitation treatment of acute cerebral infarction
XIE Lian-hong
XU Yan-hong
XU Si-qi
Abstract：Objective To evaluate the clinical efficacy and safety of monosialoganglioside(GM1 ) combined with early rehabilitation treatment of acute cerebral infarctions. Methods According to the inclusive and exclusive standards, 30 patients suffering acute cerebral infarctions between 6 hr and 72 hr were selected as a test group of GM1 combined with early rehabilitation treatment on acute cerebral infarctions. At the same time, other 30 patients were also selected as a control group. Clinical efficacy was evaluated according to changes of NIHSS and Barthel scores between two groups on the 21st day and 90th day. Results There was a significant difference of NIHSS scores between the test group and the control group( P ＞ 0.05 )on the 21st day and 90th day. There was also a significant difference of Barthel scores between the test group and the control group(P ＞0.01 ). No significant adverse reaction was observed. Conclusion GM1 combined with early rehabilitation therapy is an effective method of improving the neurological function impairment of acute cerebral infarction patients.
Keywords：Acute cerebral infarctionGangliosides GM1Early rehabilitationEffectivenesstreatment
Publication Date：2010-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)