Investigation of correlation between acute coronary syndrome and high sensitivity C-reactive protein
XU-Hui
MENG Zhao-bin
Abstract：Objective To investigate the relation among triglyce ride (TG), low density lipoprotein cholesterol(LD-C) and high sensitivity C reactive protein(hs-CRP) in acute coronary syndrome(ACS). Methods A total of 132 coronary heart disease patients which were divided as ACS and stable coronary heart dis-ease(SCHD)groups and 65 cases of the health physical exam inees were enrolled as the controls. The levels of hs-CRP, TG,HDL-C and LDL-C among the three groups were analyzed. Results The levels of hs-CRP of patients in ACS and SCHD groups were significantly higher than those in controls group(P ＜0.05). The level of hs-CRP in ACS group was obviously higher than that in SCHD group( P ＜0.01 ). There was a significant correlation between the concentration of hsCRP and TG( r = 0.62 ,P ＜ 0.01 ); there was a significant correlation between hs-CRPand LDL-C ( r =0.41, P ＜ 0.01 ); however there was a significantly negative correlation between hs-CRP and HDL-C ( r = -0.54, P ＜0.01 ). Conclusions The hs-CRP level in patients with acute coronary syndrome is obviously increased. hs-CRP is positively correlated with acute coronary syndrome, hs-CRP is the unstable sign of atheromatous plaque.
Keywords：C-reactive proteinAcute coronary syndromeHigh density lopoprotein choelsterolLow density lipoprotein cholesterol
Publication Date：2010-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)