Study of citalopram on treatment of pathological crying after cerebral infarction
YI Xu-hua
LONG Jun
LIU Li-juan
YIN Jun-lei
LIN Chun-yan
Abstract：Objective To investigate the efficacy of citalopram on treatment of pathological crying after cerebral infarction.Methods Fifty-two patients with pathological crying symptoms after cerebral infarction were randomly divided into two groups:citalopram treatment group (27 cases) and control group (25cases).Control group had conventional cerebrovascular disease treatment.Citalopram treatment group was treated with citalopram 20 mg/day for 3 months.The response rates and Hasegawa Dementia Scale (HDS) between two groups at the end of treatment were compared.Results There were significant differences in the response rates (88.9% and 36%,respectively) and HDS(8.43±2.21 and 6.24±2.02,respectively) between citalopram group and control group after treatment (P＜0.01).Conclusions The study shows that citalopram is effective for treating pathological crying after cerebral infarction.Citalopram can not only control pathological crying,but also improve cognitive function in patients with cerebral infarction.
Keywords：Cerebral infarctionPathological cryingTreatmentCitalopram
Publication Date：2010-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)