Therapeutic effect of interventional injecting antiphthisic gel on multi-drug resistant cavernous pulmonary tubercu-losis
WANG Jun
ZHANG Peng
Abstract：Objective To investigate therapeutic effect of interventional injecting antiphthisic gel through fiberbronchoscope on multi-drug resistant cavernous pulmonary tuberculosis (MDR-TB). Methods Totally 89 pa-tients (treatment group) with cavernous pulmonary MDR-TB were treated with both injecting antiphthisic gel through fiberbronchoscope catheter and routine chemotherapy; 91 cases in the control group were only given routine general chemotherapy. Results After 3,6, 18 months treatment, the sputum negative conversion rates in treatment group was 62.92%, 76.40% and 88.76% respectively, which was significantly higher than those in control group (26.37% ,42.86% and 56.04% ) respectively (P<0.01). After 18 months treatment, the effective rate in treat-ment group was 93.26% and cavity closure rate was 41.57%, which were significantly higher than those in control group (63.74% and 15.38%) respectively (P<0.01). Conclusions The therapeutic effect of MDR-TB treated with intervention injecting antiphthisic gel in cavity by fiberbronchoscope and routine chemotherapy is superior to routine chemotherapy alone.
Keywords：TuberculosislungMycobacterium tuberculosisDrug resistancemicrobionMulti-drug resistant tuberculosisAntituberculotic therapyIntervention therapyFiberbronchoscope
Publication Date：2010-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 315-317 )