Effect of Atorvastatin combined with Ginkgo Biloba Extract on carotid atherosclerotic plaque and blood lipid
CHEN Hai
YUAN Li
FANG Ling
WEI Da-you
NI Fu-wen
Abstract：Objectives To observe the influence of Atorvastatin and Ginkgo Biloba Extract (GBE) on the relative carotid ultrasonic indexes and blood lipid in patients with carotid atherosclerotic plaque. Methods A total of 206 cases patients who had been detected the carotid atherosclerotic plaque by ultrasound were divided into 4 groups. There were 50 cases in control group, 52 cases in Atorvastatin group, 53 cases in GBE group and 51 cases in Atorvastatin combined with GBE group. Only western medicine was used for basic treatment in the control group,but Atorvastatin, GBE and Atorvastatin combined with GBE were respectively used in the other three groups. The in-tima-media thickness (IMT) and changes of plaque area and blood lipid in carotid arteries before and after the treat-ment were observed for 6 months. Results The quantitative changes of carotid atherosclerotic plaque and blood fats in Astorvastatin group, GBE group and Atorvastatin combined with GBE group were all lower than those in the con-trol group(P <0.05). Furthermore the quantitative change was mostly significant in the Atorvastatin combined with GBE group(P<0.05). Conclusions Both Atorvastatin and GBE can reduce carotid atherosclerotic plaque. Fur-thermore the combination of two drugs shows high therapeutic effects.
Keywords：Carotid atheresclerosisAtorvastatinGinkgo Biloba Extract
Publication Date：2010-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 220-222 )