The clinical observation of postoperative analgesia with flurbiprofen axetil injection combined with sufentanyl
ZHANG Yan-fei
LAI Zhong-meng
CHEN Wen-hua
Abstract：Objectives To study the analgesia effect of flurbiprofen axetil injection combined with sufenta-nyl. Methods Sixty patients with 1-2 degree(WHO/ISH) hypertension were randomly divided into 3 groups with 20 cases in each group after geneal anaesthesia. Group A was given Sufentanyl 100 μg diluted to 100 ml via PCIA.Group B was given sufentanyl 50μg and flurbiprofen axetil injection 100 mg diluted to 100 ml via PCIA. In Group C only pohtidine was given. The efficacy and complications were observed. Heart rate(HR), Blood pressure(BP),Saturation of pulse oxygen (SPO_2) , Visual Analog Scale(VAS) and Ramesay score at defined time points (before anesthesia and 10 min, 1,6,12,24,48 h after anesthesia) were compared. Results The VAS of group C was high-er than those of group A and B 1,6,12,24 h after anesthesia (all P < 0.05). Ramesay score: A > B > C. The rate of using other drugs to control BP was as follows: Group A: 5%, Group B:10%, Group C: more than 45%.Conclusions Intravenous postoperative analgesia using flurbiprofen axeyii injection combined with sufentanyl has a better analgesic effect in patients than using Pethiding alone. The new strategy can reduce sufentanyl usage and the side effects and relieve changes of haemodvnamics.
Keywords：HyrertensionFlurbiprofen axeyilSufentanyAnalgesia
Publication Date：2010-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 207-209 )