Clinical study of human spermatozoa acrosin activity and spermatozoa nucleopratein transition and superox-ide dismutase of necrospermia
Abstract：Objective To explore the possible therapeutic mechanism of FUFANGXUANJU Capsule and Jujing granulation on necrospermia. Methods Computer assisted sperm analysis、spermatozoa acrosin activity、spermato-zoa nueleoprotein transition and superoxide dismutase(SOD) activity in seminal plasma were performed in 69 cases of necrospermia. The changes of sperm parameters、spermatozoa acrosin activity、spermatozoa nucleoprotein transition and SOD activity before and after the treatment with FUFANGXUANJU Capsule and Jujing granulation were ob-served. 21 men on normal fertility were enrolled as the control group. Results Compared with pre-treatment, there was no significant change in sperm concentration、spermatozoa nucleoprotein transition and the activity of SOD (P> 0.05). But rapid motility、forward motility、percent necrospermia and spermatozoa acrosin activity changed signifi-cantly after treatment (P<0.01). Conclusion FUFANGXUANJU Capsule and Jujing granulation can significantly improve sperm viability in patients with necrospermia. However, the excellent effects of FUFANGXUANJU Capsule and Jujing granulation are relted to the changes of SOD activity. Examination of spermatozoa acrosin activity and spermatozoa nucleoprotein transition are valuable for necrospermia but the change of SOD activity is not involed.
Keywords：NecrospermiaSperm paremetersPermatozoa acrosin activitySpermatozoa nucleopro-tein transitionSuperoxide dismutase
Publication Date：2009-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 958-960,前插2 )