Clinical significance and diversification of plasma P-selectin and platelet count in patients with ulcerative colitis
WANG Bing-ying
JIANG Xue-liang
Abstract：Objective To study the clinical significance and diversification of plasma P-selectin and plate-let count in patients with ulcerative colitis (UC). Methods The levels of plasma P-selectin were detected by enzyme-linked immunosorbnent assay; the platelet count was detected by blood cell counting instrument in patients with UC (n = 45) and healthy people recieving medical examination during the same period (n = 20). Results With the progress of UC, the plasma P-selectin and platelet count in patients with UC gradually increased (P <0.01, P < 0.05). The levels of plasma P-selectin in the active UC group were significandy higher than those in the control group (P <0.01), significantly higher than those in the remittent UC group(P <0.01). The platelet count in the active UC group were significantly higher than that in the control group (P < 0.01) and significantly higher than that in the remittent UC group (P<0.01). Conclusion P-selectin is closely related to the incidence of UC and the progress of disease. Combined detection of plasma P-selectin and platelet count in patients with UC has ref-erence value for the disease estimation and the efficacy assessment.
Keywords：Ulcerative colitisP-selectinPlatelet count
Publication Date：2009-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：2( 870-871 )